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美国戴安Dionex DNASwift SAX-1S 066766 生物色谱柱

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产品名称: 美国戴安Dionex DNASwift SAX-1S 066766 生物色谱柱
产品型号: 066766
产品展商: 美国戴安Dionex
产品文档: 无相关文档

简单介绍

戴安公司生产的仪器主要有离子色谱仪、高效液相色谱仪、快速溶剂萃取仪和氨基酸直接分析仪。其中离子色谱仪凭借着雄厚的技术优势和方法已广泛地应用于各个领域,其市场占有率达80%。全球与离子色谱相关的文章有90%均出自戴安公司生产的离子色谱仪。   戴安公司的快速溶剂萃取仪15分钟之内仅用15毫升溶剂既可完成对10g样品的萃取,该技术已在环境、**、食品和聚合物工业等领域得到广泛应用。


美国戴安Dionex DNASwift SAX-1S 066766 生物色谱柱  的详细介绍

DNASwift SAX-1S

The DNASwift SAX-1S is a strong anion-exchange column that provides exceptionally high resolution for the purification of oligonucleotides. The exceptionally high resolution provides superior purity and yields compared to other ion-exchange or reversed-phase columns available. The DNASwift column is ideal for therapeutic and diagnostic research, which have very high purity and yield oligonucleotides purification requirements.

  • Highest resolution for oligonucleotide purification available, providing high purity and yields.
  • Exceptionally high capacity provides exceptionally high yields with high purity.
  • Refined selectivity, as with the DNAPac® column, for high resolution
  • Compatible with high pH, solvents, and high temperatures.

The DNASwift monolith column is specifically designed to provide exceptionally high resolution, laboratory-scale purification of oligonucleotides by anion-exchange chromatography. The use of oligonucleotides in therapeutic and diagnostic research is rapidly expanding. Oligonucleotides for these areas of research must be of the highest purity. DNASwift monolith columns provide high resolution and capacity, resulting in superior purity and yield compared to other ion-exchange and revered-phase columns available.

The DNASwift column is a unique porous polymer monolith specifically designed for superior performance in oligonucleotide purification. The column is a pressure and chemically stable monolith support coated with functionalized latex nanobeads. These latex nanobeads, beads with strong anion-exchange functional groups, optimized for oligonucleotide separations, are similar to those of the industry leading DNAPac columns. Similarly, the nanobeads contribute to the DNASwift column's exceptionally high resolution and selectivity control. The monolith, a polymer cylinder with interconnected flow through channels, provides fast mass transfer which contributes to the exceptionally high resolution of the DNASwift column. The porous monolith also offers low back pressure, allowing increased flow rates with minimal loss of resolution. The combination of functionalized latex nanobeads and monolith technology results in the DNASwift column having very high capacity, exceptionally high resolution, and refined selectivity control, which results in superior purity and yield of full length oligonucleotide products purified from crude oligonucleotide samples. This makes the DNASwift column ideal for oligonucleotide, therapeutic, and diagnostic research. Additionally, it provides DNASwift columns with the capability to successfully purify difficult oligonucleotide products.

DNASwift SAX-1S  Specifications
Surface chemistry Quaternary amine
Column dimension 5 × 150 mm
Base matrix Polymethacrylate
Oligonucleotide binding capacity ~20 mg/mL 20-mer
Total binding capacity per column ~50 mg 20-mer
Bed height 130 mm
Bed volume 2.5 mL
pH Range 6–12.4 for operation 2–14 for cleaning NOTE: [Salt]≥Equimolar to [NaOH] required
Recommended Ffow rate 0.5–2.5 mL/min 
Maximum flow rate 3 mL/min
Operating column pressure ≤ 1500 psi 10.3 MPa
Maximum operating temperature 85 °C
Solvent compatibility Most common organic solvents (e.g., CH3CN, CH3OH)
Ordering Information
DNASwift SAX-1S Monolith Column (5 x 150 mm) 066766

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